MELANOTAN1(MT1) 10MG
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MELANOTAN1(MT1) 10MG

$5.80

SKU: OR-PEP-MT1-10-MG-1

MELANOTAN1(MT1) 10 MG

PER VIAL : 10 mg

Price is base on: 1 vial

RAW MATERIALS ARE MADE BY THE USA

The chemicals/materials/peptides for sale here are intended for laboratory and research use only, unless otherwise explicitly stated. They are not intended for human ingestion, use, or for use in products that may be ingested.

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Product Name: MELANOTAN1(MT1)
 Unit size: 10 mg
 CAS NO.:

75921-69-6

 Synonyms:

Melanotan; Melanotan-1; Melanotan I; CUV1647; EPT1647; NDP-MSH; [Nle4, D-Phe7]α-MSH [Nle4, D-Phe7]-α-MSH Melanotan

 Sequence:

Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2

 Purity: ≥99% (HPLC)
 Physical State: Lyophilized Powder
 Solubility: Soluble in water or 1% acetic acid
 Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C.

Melanotan1 10mg-MT1 10mg

Melanotan-1 Peptide Amino Acid Sequence:
Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Molecular formula: C78H111N21O19
Molar Mass: 1646.845
CAS number: 75921-69-6
Synonyms: Melanotan; Melanotan-1; Melanotan I; CUV1647; EPT1647; NDP-MSH; [Nle4, D-Phe7]α-MSH
[Nle4, D-Phe7]-α-MSH Melanotan

price is base on per 20vial

Important Notification: All of our products and services listed in this website are for research or production use only, not for direct human use.

Melanotan 1 (also referred to as Afamelanotide) is a synthetic peptide variant of a peptide hormone, called alpha-Melanocyte stimulating hormone or MSH that is naturally produced in the body and is responsible for stimulating melanogenesis, a peptide process for pigmentation of the skin. Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan-1 sunless skin tanning effects. While Melanotan 2 and PT-141 have been studied at length as a potential remedies for the treatment of sexual dysfunction, Melanotan-1 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

Both Melanotan-1 and Melanotan 2 are analogs of the peptide hormone alpha-melanocyte stimulating hormone (α-MSH) that tend to induce skin tanning. Unlike Melanotan 1, Melanotan 2 has been shown to have aphrodisiac properties, the additional effect of increasing libido. Melanotan-1 is a non selective agonist of the melanocortin receptors (MC1R,MC3-5R). As an analogue of α-MSH, its mechanism of action is biomimicry of the natural mammalian tanning process.

The Development of Melanotan 1

The initial creation of the Melanotan 1 peptide tanning analogue can be credited to the University of Arizona. During the course of study aimed at developing a defense against skin cancer, focus was placed on developing a method of stimulating natural melanogenesis, or the natural production of melanin in the skin, without direct exposure to the potentially harmful ultraviolet radiation in sunlight. Initially, University of Arizona researchers attempted to directly administer the naturally occurring hormone alpha-MSH in order to elicit this desired result. Although this strategy exhibited promising results, it was determined that the naturally occurring MSH had a prohibitively short half-life to be of realistic use as a therapeutic remedy. However, the positive results gleaned from MSH administration encouraged further research into the development of Melanotan 1, which exhibits similar effects whilst possessing an extended half-life for functional therapeutic utilization. The researchers, headed by Victor J. Hruby and Mac E. Hadley, found a peptide, [Nle4, D-Phe7]-α-MSH, that was approximately 1,000 times more potent than natural α-MSH. They named this new peptide molecule “Melanotan” (later Melanotan-1).


 

Melanotan-1 Mechanism of Action – How it Works!

Melanotan produces its photoprotective effects by triggering a ‘signaling cascade’ via its activation of the MC1R on melanin-producing cells known as melanocytes. Upon Melanotan binding with the MC1R on the surface of melanocytes in the epidermal layer of the skin, it begins a series of actions and reactions that result in melanocytes favoring the production of eumelanin (photoprotective black/brown pigment). The initial binding activates the MC1R leading to the activation of adenylate cyclase (AC) and stimulation of the production of cyclic adenosine monophosphate (cAMP). cAMP in turn activates protein kinase A (PKA) resulting in the phosphorylation of the cAMP response element-binding (CREB). Phosphorylated CREB will bind to the cAMP response element (CRE) on the microphthalmia-associated transcription factor (MITF) gene leading to the synthesis of the MITF protein. MITF has the ability to activate several genes by binding to them, including the MC1R gene and the genes involved in melanogenesis. This results in increased concentrations of the melanogenic enzymes within the melanocyte.

OUR ADVANTAGE

24x7 CUSTOMER SUPPORT

  • OUR WAREHOUSES are in Europe, USA, SINGAPORE, VIETNAM, THAILAND, UK, MALAYSIA

  • 24×7 online customer services 

  • HPLC and MS records for all of our products

  • The R&D center in the USA

  • OVER two decades experience in chemical and peptide industry

  • Producing as OEM /ODM with our customer labels

  • Accepting different currencies

  • 98.3% customer satisfaction in two decades

PACKING

Shipping

Our delivery solutions are as follow:
– Via Express services such as FedEx, EMS, DHL, TNT, USPS priority, UPS
– E-Commerce post service from the USA , Europe, Hongkong
– International Air freights for heavy packages over 50kg
– International ocean and rail freight for heavy packages over 200kg

ORANGE PEPTIDE FACTORY & LAB

OVER 10000 M2 production plant

We provide high-quality peptide synthesis service with a 99% peptide synthesis success rate, which is well above the industry standard of 75%. We are committed to Total Quality Management (TQM) to ensure our customers’ complete satisfaction. TQM includes MS and HPLC analyses performed after the completion of peptide synthesis, purification, and QC (quality control) steps. These analyses are followed by independent QA (quality assurance) procedures, which double guarantee the highest quality possible for every delivered peptide.

FAQ: 

A peptide that I purchased recently has less powder in it than others I’ve gotten. Does this mean it doesn’t have the right MG?

Peptides due to their nature come in a variety of sizes and shapes. Normally after the lyophilization process has completed we have a peptide that is in a perfect cake. However, there are times when it may break in transit or simply appear differently. This is no way affects the quality or potency of the product. It is simply an aesthetic issue. While we do try to always present a product that looks perfect, on occasion, this isn’t possible. Proteins such as IGF1 are very large in size and due to the requirement of a buffer will appear larger in size than a bpc157 or pt141. This is also normal.

What are the Purity Levels Of the peptides you Sell?

We will never sell a peptide that is less than 98% in purity from our catalog section. Many of our smaller peptide chains are well into the 99% purity range. We have manufacturing abilities that are quite often beyond the scope of smaller companies and therefore are able to achieve very high purity levels. Proteins such as IGF-1 LR3 are always receptor grade and always above 98% purity.

What are your products used for?

Peptides and Research serums are manufactured and sold to be used in a laboratory research setting. None of our products are intended for, nor are they manufactured for, diagnostic or therapeutic purposes in humans. Strong Peptide reserves the right to require additional verification of proper intent prior to fulfilling orders. Any orders that we feel aren’t for the specific intended purpose laid out in our Terms and Conditions will be denied.  Truthfully, if you are asking this question then you shouldn’t be ordering from us.

Will you test your powders after production?

Yes, We will test per batch in our laboratory, we will have HPLC, MS record for all of our products. We will check our peptides vial by vial before delivery.

Do you have GMP lab ?

Yes, we have GMP lab, and we have a fully automatic production line. We could produce all of our peptides with the automtic sealing machine. We are able to offer vacuum sealed vials.

Do you have wholesale prices?

We have special prices for our distributors and wholesale customers. We could produce as OEM with customized box, label, cap colors, For more information please contact us

CONTACT US: 


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